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Simon Elsässer

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Works

TitleDOIPublished date
G-quadruplex profiling in complex tissues using single-cell CUT&Tag10.1101/2025.04.03.6471012025-04-05
Multiplexed chromatin immunoprecipitation sequencing for quantitative study of histone modifications and chromatin factors10.1038/s41596-024-01058-z2025-03
Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response10.1101/2024.12.08.6274092024-12-09
A large-scale sORF screen identifies putative microproteins and provides insights into their interaction partners, localisation and function10.1101/2023.06.13.5448082023-06-13
Dual stop codon suppression in mammalian cells with genomically integrated genetic code expansion machinery10.1101/2023.03.26.5342792023-03-27
minute: A MINUTE-ChIP data analysis workflow10.1101/2022.03.14.4843182022-03-17
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-4310.1038/s41467-022-28822-72022-03-09
Genome-wide mapping of G-quadruplex structures with CUT&Tag10.1093/nar/gkab10732022-02-22
Distinct transcription kinetics of pluripotent cell states10.15252/msb.2021104072022-01
Revisiting sORFs: overcoming challenges to identify and characterize functional microproteins10.1111/febs.157692022-01
Polycomb Repressive Complex 2 shields naïve human pluripotent cells from trophectoderm differentiation10.1101/2021.08.21.4572152021-08-22
Engineered human induced pluripotent cells enable genetic code expansion in brain organoids10.1101/2021.06.24.4495762021-06-24
Correction to: Towards policies that capture the expected value of biomolecular diversity for drug discovery, human health, and well-being10.1007/s42977-020-00045-12021-06-23
Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-210.1038/s41467-021-23893-42021-06-17
Newly synthesized RNA Sequencing Characterizes Transcription Dynamics in Three Pluripotent States10.1101/2021.06.11.4480162021-06-13
Towards policies that capture the expected value of biomolecular diversity for drug discovery, human health, and well-being10.1007/s42977-020-00043-32021-06-07
Genome-wide mapping of G-quadruplex structures with CUT&Tag10.1101/2021.04.25.4413122021-04-26
Universal Single-Residue Terminal Labels for Fluorescent Live Cell Imaging of Microproteins10.1021/jacs.0c095742020-11-25
An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility10.1038/s41467-020-18863-12020-10-09
A translational multiplex serology approach to profile the prevalence of anti-SARS-CoV-2 antibodies in home-sampled blood10.1101/2020.07.01.201439662020-07-02
Sirtuin-1 Sensitive Lysine-136 Acetylation Drives Phase Separation and Pathological Aggregation of TDP-4310.1101/2020.05.26.1043562020-05-26
An embryonic stem cell-specific heterochromatin state allows core histone exchange in the absence of DNA accessibility10.1101/2020.05.22.1107422020-05-22
MINUTE ChIP v110.17504/protocols.io.8nkhvcw2019-10-23
Quantitative multiplexed ChIP reveals global alterations that shape promoter bivalency in ground state embryonic stem cells10.1101/5570822019-03-06
Dual Bioorthogonal Labeling of the Amyloid-β Protein Precursor Facilitates Simultaneous Visualization of the Protein and Its Cleavage Products10.3233/JAD-1908982019
Evochromo: Towards a synthesis of chromatin biology and evolution10.1242/dev.1789622019
Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells10.1016/j.celrep.2019.08.0462019
Methanomethylophilus alvus Mx1201 Provides Basis for Mutual Orthogonal Pyrrolysyl tRNA/Aminoacyl-tRNA Synthetase Pairs in Mammalian Cells10.1021/acschembio.8b005712018-11-16
Methanomethylophilus alvus Mx1201 provides basis for mutual orthogonal pyrrolysyl tRNA/aminoacyl-tRNA synthetase pairs in mammalian cells10.1101/3717572018-07-19
Generation of stable amber suppression cell lines10.1007/978-1-4939-7574-7_152018
Biodiversity, drug discovery, and the future of global health: Introducing the biodiversity to biomedicine consortium, a call to action10.7189/jogh.07.0203042017-11
Evolution of epigenetic chromatin states.10.1016/j.cbpa.2017.10.0012017-10
Elsässer et al. reply.10.1038/nature232782017-08
Network analyses identify liver-specific targets for treating liver diseases.10.15252/msb.201777032017-08
Genetic code expansion in stable cell lines enables encoded chromatin modification.10.1038/nmeth.37012016-02
Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes10.1021/jacs.5b076272016
Critical Role of Histone Turnover in Neuronal Transcription and Plasticity.10.1016/j.neuron.2015.06.0142015-07
Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells.10.1038/nature143452015-06
DAXX co-folds with H3.3/H4 using high local stability conferred by the H3.3 variant recognition residues10.1093/nar/gku0902014
Efficient multisite unnatural amino acid incorporation in mammalian cells via optimized pyrrolysyl tRNA synthetase/tRNA expression and engineered eRF110.1021/ja50697282014
Genetic encoding of photocaged cysteine allows photoactivation of TEV protease in live mammalian cells10.1021/ja412191m2014
Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal10.1038/nbt.28602014
A common structural theme in histone chaperones mimics interhistone contacts10.1016/j.tibs.2013.04.0022013
Hira-dependent histone H3.3 deposition facilitates prc2 recruitment at developmental loci in ES cells10.1016/j.cell.2013.08.0612013
DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition10.1038/nature116082012
Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events10.1038/nsmb.23102012
Towards a mechanism for histone chaperones10.1016/j.bbagrm.2011.07.0072012
Anti-apoptotic Bcl-2 fails to form efficient complexes with pro-apoptotic Bak to protect from Celecoxib-induced apoptosis10.1016/j.bcp.2010.09.0022011
New epigenetic drivers of cancers10.1126/science.12032802011
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres10.1073/pnas.10088501072010
Differential effects of anti-apoptotic Bcl-2 family members Mcl-1, Bcl-2, and Bcl-xL on Celecoxib-induced apoptosis10.1016/j.bcp.2009.07.0212010
Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions10.1016/j.cell.2010.01.0032010
HIRA and Daxx constitute two independent histone H3.3-containing predeposition complexes10.1101/sqb.2010.75.0082010
New functions for an old variant: No substitute for histone H3.310.1016/j.gde.2010.01.0032010
Importance of Bak for celecoxib-induced apoptosis10.1016/j.bcp.2008.08.0122008
In situ observation of protein phosphorylation by high-resolution NMR spectroscopy10.1038/nsmb.13952008

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