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fusion gene

Research Topic

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This is a research topic created to provide authors with a place to attach new problem publications.

Research topics above this in the hierarchy

  • genetic disease

Research problems linked to this topic

  • Cancer gene therapy has been of great challenge in achieving maximal high levels of specificity and more rational efficiency in target cancer cell.
  • Genome rearrangements, a hallmark of cancer, can result in gene fusions with oncogenic properties.
  • The high immunogenicity of recombinant adenoviral vectors is one of the major issues in the field of gene therapy.
  • Ewing family tumors (EFT), classically Ewing's sarcoma and peripheral primitive neuroectodermal tumor, share a common class of tumor-specific fusion genes thought to be key mediators of tumor biology.

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