M S

Matt Spick

Employment

Organisation	Role	Department	Start date	End date
Springer Nature (Germany)	Associate Editor, Metabolism Section	Not specified	2024-06-26
University of Surrey	Lecturer in Health and Biomedical Data Analytics	Not specified	2023-01-01

Education

No history available.

Works

Title	DOI	Published date
AI-enabled exploitation of open science: a response to Zil-E-Ali on safeguarding data research integrity	10.1016/j.jclinepi.2026.112251	2026-07
Impact of Daily Rhythms and Postprandial Responses on the Plasma Metabolome	10.3390/ijms27135669	2026-06-23
A Systematic Evidence Map of FAIR Compliance in Open-Access Metabolomics Research: Results from a Pilot Study	10.3233/SHTI260374	2026-05-21
Quantifying new threats to health and biomedical literature integrity from rapidly scaled publications and problematic research	10.1016/j.jclinepi.2026.112203	2026-05
Who chooses open peer review and is it an indicator of article quality? An observational study of PLOS journals.	10.31222/osf.io/2b7z5_v1	2026-04-10
Drastic changes in collaboration networks and publication patterns in research using the CDC WONDER dataset	10.64898/2026.01.13.26343992	2026-01-15
Safeguarding Open Science from exploitative practices	10.1371/journal.pmed.1004851	2025-12-11
Dramatic increases in redundant publications in the Generative AI era	10.1186/s12916-025-04569-y	2025-12-09
A systematic evidence map of FAIR compliance in open-access metabolomics publications	10.17605/OSF.IO/FP2EM	2025-09-19
Meeting the challenges posed by mass-produced manuscripts and click-data science	10.3897/ese.2025.e165043	2025-09-18
Dramatic increases in redundant publications in the Generative AI era	10.1101/2025.09.09.25335401	2025-09-12
Mapping the evidence of the effects of environmental factors on the prevalence of antibiotic resistance in the non-built environment	10.1016/j.envint.2025.109634	2025-08
Machine Learning Applied to NHS Electronic Staff Records Identifies Key Areas of Focus for Staff Retention	10.3390/admsci15080297	2025-07-29
Quantifying new threats to health and biomedical literature integrity from rapidly scaled publications and problematic research	10.1101/2025.07.07.25331008	2025-07-09
Explosion of formulaic research articles, including inappropriate study designs and false discoveries, based on the NHANES US national health database	10.1371/journal.pbio.3003152	2025-05-08
Variable hyperthyroidism outcomes related to different treatment regimens: an analysis of UK Biobank data	10.1530/ETJ-24-0393	2025-04-02
Identifying Key Weather Factors Influencing Human Salmonellosis: A Conditional Incidence Analysis in England, Wales, and the Netherlands	10.1016/j.jinf.2025.106410	2025-02
Challenges and opportunities for statistical power and biomarker identification arising from rhythmic variation in proteomics	10.1038/s44323-024-00020-2	2025-01-01
Single-Cell Lipidomics: An Automated and Accessible Microfluidic Workflow Validated by Capillary Sampling	10.1021/acs.analchem.4c03435	2024-11-05
Observations from Statistical Review Editors: A Commentary	10.1016/j.xjidi.2024.100302	2024-11
Challenges in Lipidomics Biomarker Identification: Avoiding the Pitfalls and Improving Reproducibility	10.3390/metabo14080461	2024-08-19
Rhythmic variation in proteomics: challenges and opportunities for statistical power and biomarker identification	10.1101/2024.06.28.601121	2024-06-28
Multi-omic diagnostics of prostate cancer in the presence of benign prostatic hyperplasia	10.1016/j.heliyon.2023.e22604	2023-12
Single-Cell Lipidomics Using Analytical Flow LC-MS Characterizes the Response to Chemotherapy in Cultured Pancreatic Cancer Cells	10.1021/acs.analchem.3c02854	2023-10-03
Meta-Analysis of COVID-19 Metabolomics Identifies Variations in Robustness of Biomarkers	10.3390/ijms241814371	2023-09-21
Impact of COVID-19 on the host lipidome and metabolome by mass spectrometry	10.15126/thesis.900780	2023-08-31
A Novel Blood Proteomic Signature for Prostate Cancer	10.3390/cancers15041051	2023-02-07
Metabolomic Analysis of Plasma in Huntington's Disease Transgenic Sheep (Ovis aries) Reveals Progressive Circadian Rhythm Dysregulation	10.3233/JHD-220552	2023
Viral pIC-pocketing: RSV sequestration of eIF4F Initiation Complexes into bi-phasic biomolecular condensates	10.1101/2023.04.14.536931	2023
Multi-Omics Reveals Mechanisms of Partial Modulation of COVID-19 Dysregulation by Glucocorticoid Treatment	10.3390/ijms232012079	2022-10-11
Metabolomics Markers of COVID-19 Are Dependent on Collection Wave	10.3390/metabo12080713	2022-07-30
Systematic review with meta-analysis of diagnostic test accuracy for COVID-19 by mass spectrometry	10.1016/j.metabol.2021.154922	2022-01-01
An integrated analysis and comparison of serum, saliva and sebum for COVID-19 metabolomics	10.1038/s41598-022-16123-4	2022
Untargeted saliva metabolomics by liquid chromatography-Mass spectrometry reveals markers of COVID-19 severity	10.1371/journal.pone.0274967	2022
Loss of a pyoverdine secondary receptor in Pseudomonas aeruginosa results in a fitter strain suitable for population invasion	10.1038/s41396-020-00853-2	2021-05-01
Changes to the sebum lipidome upon COVID-19 infection observed via rapid sampling from the skin	10.1016/j.eclinm.2021.100786	2021
Thioester-Functional Polyacrylamides: Rapid Selective Backbone Degradation Triggers Solubility Switch Based on Aqueous Lower Critical Solution Temperature/Upper Critical Solution Temperature	10.1021/acsapm.0c00503	2020-06
Fully Degradable Thioester-Functional Homo- and Alternating Copolymers Prepared through Thiocarbonyl Addition-Ring-Opening RAFT Radical Polymerization	10.1021/acs.macromol.9b02497	2020-01-28

Octopus publications

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Rationale / Hypothesis

Generative AI and the Re-emergence of Lone-Author Scholarship

Generative AI may lower the costs of lone scholarship; a post-2022 shift in single authorship would be consistent with this hypothesis

Published July 1, 2026, by M. Spick, D. Maupin

Method

Detection arbitrage: the Dryad data deposition dodge

11.5% of Dryad DOIs in 2024–2026 papers fail to resolve; this may be due to deliberate abandonment of data post-publication to reduce costs or evade scrutiny.

Published May 28, 2026, by M. Spick

Rationale / Hypothesis

Co-optation of Data Availability: detection arbitrage via use of Dryad reserved DOIs

RationaleThis Hypothesis tests a specific example of the co-optation pattern described in the parent Research Problem (Spick, 2026). Dryad permits authors to generate a "reserved DOI" prior to full data deposition at a nominal cost (USD 50 at the time of writing) (Dryad | Private for Peer Review). This is intended to support embargoed data and pre-publication peer...

Published May 25, 2026, by M. Spick

Research Problem

Open Science indicators: co-optation by low-quality and mass-manufactured research as an adversarial adaptation

SummaryThe aims of Open Science are supported by a suite of metrics, which cover open data use, open peer review, code deposition, preregistration, ORCIDs, reporting checklists and data availability statements. These function as trust signals for editors, reviewers and readers. Any trust signal, however, can be mimicked. It is therefore reasonable to hypothesise th...

Published May 25, 2026, by M. Spick

Results / Sources

Evidence of increasing ‘redundant publications’ in the generative AI era

Results of our workflow to identify redundant publications in NHANES and how GenAI facilitates this

Published May 12, 2026, by D. Maupin, T. Suchak, A. Barnett, M. Spick

Method

Investigating growth in ‘redundant publications’ generated through the assistive use of Generative AI

Methodology used to identify redudnant publications present in the National Health and Nutrition Examination Survey (NHANES) dataset.

Published April 29, 2026, by D. Maupin, T. Suchak, A. Barnett, M. Spick

Analysis

From Open Data to Automated Paper: Analysis of Agentic AI Outputs

Agentic AI can generate credible papers from FAIR data in 30 minutes at near-zero cost, posing a systemic threat to research integrity and Open Data practices.

Published March 7, 2026, by M. Spick, T. Suchak, A. Barnett

Results / Sources

The 30 minute manuscript: an example scientific paper by AI agent

Results of an AI-generated manuscript reporting a cross-species metabolic ripening clock for eggplant and pepper, produced without human analytical input.

Published March 3, 2026, by M. Spick, T. Suchak, A. Barnett

Method

A structured workflow for adversarial manuscript generation using PRISM and open FAIR data

A method to test whether PRISM, an AI agent, can generate a plausible scientific manuscript from open data with no human analytical input or research agency.

Published February 27, 2026, by M. Spick, A. Barnett, T. Suchak

Rationale / Hypothesis

Generative AI is reducing the frictional cost of scientific manuscript production and facilitating mass-manufacture of papers

We hypothesise that GenAI is enabling industrial-scale production of AI slop scientific manuscripts, and aim to assess GenAI's adversarial capabilities.

Published February 25, 2026, by D. Maupin, T. Suchak, A. Barnett, M. Spick

Research Problem

AI-Facilitated Contamination of the Literature as a Threat to Open Science and Public Trust

Artificial Intelligence is enabling industrial-scale production of low-quality research, threatening the scientific record and also public trust in science.

Published February 22, 2026, by M. Spick